Karunanayake, C. P., McDuffie, H. H., Dosman, J. A., Spinelli, J. J., & Pahwa, P., “Occupational exposures and non-Hodgkin’s lymphoma: Canadian case-control study,” Environ Health, 2008, 7, 44. DOI: 10.1186/1476-069X-7-44.
ABSTRACT:
BACKGROUND: The objective was to study the association between Non-Hodgkin’s Lymphoma (NHL) and occupational exposures related to long held occupations among males in six provinces of Canada.
METHODS: A population based case-control study was conducted from 1991 to 1994. Males with newly diagnosed NHL (ICD-10) were stratified by province of residence and age group. A total of 513 incident cases and 1506 population based controls were included in the analysis. Conditional logistic regression was conducted to fit statistical models.
RESULTS: Based on conditional logistic regression modeling, the following factors independently increased the risk of NHL: farmer and machinist as long held occupations; constant exposure to diesel exhaust fumes; constant exposure to ionizing radiation (radium); and personal history of another cancer. Men who had worked for 20 years or more as farmer and machinist were the most likely to develop NHL.
CONCLUSION: An increased risk of developing NHL is associated with the following: long held occupations of faer and machinist; exposure to diesel fumes; and exposure to ionizing radiation (radium). The risk of NHL increased with the duration of employment as a farmer or machinist.