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Bibliography Tag: developmental impacts

Roberts and Karr, 2012

Roberts JR, Karr CJ,  “Pesticide exposure in children,” 2012, Pediatrics,  130:6.

ABSTRACT: This statement presents the position of the American Academy of Pediatrics on pesticides. Pesticides are a collective term for chemicals intended to kill unwanted insects, plants, molds, and rodents. Children encounter pesticides daily and have unique susceptibilities to their potential toxicity. Acute poisoning risks are clear, and understanding of chronic health implications from both acute and chronic exposure are emerging. Epidemiologic evidence demonstrates associations between early life exposure to pesticides and pediatric cancers, decreased cognitive function, and behavioral problems. Related animal toxicology studies provide supportive biological plausibility for these findings. Recognizing and reducing problematic exposures will require attention to current inadequacies in medical training, public health tracking, and regulatory action on pesticides. Ongoing research describing toxicologic vulnerabilities and exposure factors across the life span are needed to inform regulatory needs and appropriate interventions. Policies that promote integrated pest management, comprehensive pesticide labeling, and marketing practices that incorporate child health considerations will enhance safe use.  FULL TEXT

National Research Council, 1993

National Research Council, Committee on Pesticides in the Diets of Infants and Children,  “Pesticides in the Diets of Infants and Children,” 1993, National Academies Press, Washington DC., DOI: 10.17226/2126.  Available at:

Colborn and Carroll, 2007

Colborn, Theo, Lynn Carroll,  “Pesticides, Sexual Development, Reproduction,and Fertility: Current Perspective and Future Direction,” Human and Ecological Risk Assessment, 2007, 13:5.

ABSTRACT: Improvements in chemical analytical technology and non-invasive sampling protocols have made it easier to detect pesticides and their metabolites at very low concentrations in human tissues. Monitoring has revealed that pesticides penetrate both maternal and paternal reproductive tissues and organs, thus providing a pathway for initiating harm to their offspring starting before fertilization throughout gestation and lactation. This article explores the literature that addresses the parental pathway of exposure to pesticides. We use DDT/DDE as a model for chemicals that oftentimes upon exposure have no apparent, immediate health impacts, or cause no obvious birth defects, and are seldom linked with cancer. Their health effects are overlooked because they are invisible and not life threatening—but might have significant health, social, and economic impacts at the individual and population levels. The purpose of this article is to demonstrate the necessity to develop new approaches for determining the safety of pesticides and the need for innovative regulatory policy to protect human and environmental health. FULL TEXT

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