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Archived HHRA News Posts
  • HHRA-funded Dicamba study published in “agrochemicals”

    Dicamba and 2,4-D in the Urine of Pregnant Women in the Midwest: Comparison of Two Cohorts (2010–2012 vs. 2020–2022) Abstract Currently, there are no known human biomonitoring studies that concurrently examine biomarkers of dicamba and 2,4-D. We sought to compare biomarkers of exposure to herbicides in pregnant women residing in the US Midwest before and after the adoption of dicamba-tolerant soybean technology using urine specimens obtained in 2010–2012 from the Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-be (N = 61) and in 2020–2022 from the Heartland Study (N = 91). Specific gravity-standardized concentration levels for each analyte were compared between the cohorts, assuming data are lognormal and specifying values below the LOD as left-censored. The proportion of pregnant individuals with dicamba detected above the LOD significantly increased from 28% (95% CI: 16%, 40%) in 2010–2012 to 70% (95% CI: 60%, 79%) in 2020–2022, and dicamba concentrations also significantly increased from 0.066 μg/L (95% CI: 0.042, 0.104) to 0.271 μg/L (95% CI: 0.205, 0.358). All pregnant individuals from both cohorts had 2,4-D detected. Though 2,4-D concentration levels increased, the difference was not significant (p-value = 0.226). Reliance on herbicides has drastically increased in the last ten years in the United States, and the results obtained in this study highlight the need to track exposure and impacts on adverse maternal and neonatal outcomes. Keywords: pesticide; exposure; 2,4-dichlorophenoxyacetic acid; human biomonitoring You can read the paper here.

  • Crop-killing Weeds Advance Across US as Herbicides Lose Effectiveness

    Farmers say they are losing their battle with weeds at a time when growers are grappling with inflation and extreme weather linked to climate change. Crop-killing weeds such as kochia are advancing across the U.S. northern plains and Midwest, in the latest sign that weeds are developing resistance to chemicals faster than companies including Bayer and Corteva  can develop new ones to fight them. In many cases weeds are developing resistance against multiple herbicides, scientists said. Read the Reuters report here.  Read an earlier post by the HHRA board chair on the problem of resistant weeds here.

  • Heartland Health Research Alliance logo Help Lead this Worthy Cause: The HHRA is Recruiting Board Members

    We are publicly recruiting for board positions to ensure that we move beyond our immediate networks and honor our ongoing commitment to creating a board that is diverse in its composition, inclusive in its culture, and equity-focused in its approach to how it views its mission, its work, and the communities it serves. Our board members are the fiduciaries who steer the HHRA toward a sustainable future by adopting sound, ethical, and legal governance and financial management policies, as well as by making sure the HHRA has adequate resources to advance its mission. The Heartland Health Research Alliance (HHRA) is a 501(c)(3) organization founded in 2020 and dedicated to creating a new future in which cultivating health is the priority of farming. Our mission is to help inform the decisions shaping agriculture by advancing research on the health effects of food and farming. The HHRA seeks to fill vacancies on its board with qualified volunteers who, in addition to the standard roles and responsibilities (see below) of a board member, will be active advocates and ambassadors for the organization. Preferred qualifications 1. Professional experience in public health, medical research, epidemiology, toxicology, or organic farming, 2. A network or experience, or both, that may facilitate grant seeking and fundraising. 3. Commitment to the scientific method and the integrity of research. Essential information 1. The board of the HHRA is a volunteer board. 2. Each term is for three years, to which members can be re-elected once. 3. The board meets four times a year via the Internet. Expectations The HHRA expects each board member to honor the HHRA values and mission, act in the best interest of the HHRA, prepare for the board meetings by reading the agenda and reports, participate in the board meetings, and identify personal and professional connections for HHRA fundraising, grant-seeking, and policy influence. Process 1. To apply to volunteer, please send your CV and a one-page cover letter providing your name, contact information, and a description of either which of the preferred qualifications (above) you will bring to the HHRA or how your unique qualifications can help the HHRA.  Send these materials to Russell K. King, HHRA executive director, at rking@hh-ra.org . 2. Qualified applications will be reviewed by the current board, which will vote on whether to seat a volunteer as a member. (The next board meeting is in February 2024.) 3. The recruiting process will remain open until all seats are filled. Standard board member duties 1) Board members should advance the mission of the organization Overall, spreading awareness for your mission will promote growth and empower your team to flourish in its work. 2) Board members should prepare for and attend board meetings Review the agenda in advance. Everyone should understand all matters on the agenda heading into the meeting. Participation in discussions is a big part of why you choose someone for a role on the board. Fulfilling these duties is part of acting in good faith for any board member. 3) Board members hire, set compensation for, support, and collaborate with the executive director Hiring and supporting the executive director is one of the most important board member responsibilities.  The executive director is the professional hired to as bring nonprofit leadership and operational expertise to the HRRA’s daily operations and to advice and educate the board on matters relating to nonprofit governance and operations, so this board role is crucial to the organization’s health. 4) Board members are responsible for recruiting new members Drawing on your professional and personal networks, seek new members who have needed skills and qualities that are missing from the current board. 5) Every board member must fulfill three specific core legal responsibilities. Duty of Care Attending meetings and actively participating. Communicating with the executive director and other board members. Following through on assignments.. Supporting programs. Duty of Loyalty Support HHRA’s mission. Be a loyal ambassador for HHRA’s cause. All activities and decisions should be in the best interest of the organization, not in the best interest of the individual board member. Support the HHRA executive director. Duty of Obedience Adhere to HHRA’s bylaws, policies, and board decisions.

  • Fairness and Trust in Organic Food Supply Chains

    From the British Food Journal Findings show that perceived distributional, procedural and interactional fairness mutually interact with the perceived trustworthiness of business partners and that both contribute to building personal, organisational and institutional trust. Qualitative data support the conceptual model and show that trust is a valuable relational resource that affects relationship quality and the willingness to collaborate and to take risks in times of uncertainty.   More here.

  • Heartland Study Methods Paper Published in Chemosphere

    A methods paper is about our flagship study is being published in Chemosphere, a peer-reviewed scientific journal published since 1972 by Elsevier. It publishes both original research and review articles in environmental chemistry.  We extend our thanks to the authors: Jessica Larose, Jean-François Bienvenu, Patrick Bélanger, Éric Gaudreau, Yunpeng Yu, and David M. Guise.  

HHRA Partners with CTQ Lab in Quebec

Mar 12th, 2021
Mar 12th, 2021

HHRA is pleased to announce a new partnership with the Centre de toxicologie du Québec analytical laboratory, or CTQ. This world-renowned lab will process biological samples collected through HHRA’s medical research on the public health implications of pesticide exposure. For example, urine samples from moms and babies enrolled in our flagship project The Heartland Study will soon be heading north to be tested for glyphosate, the most-commonly used herbicide in the US.

While our scientists had hoped to work with the Centers for Disease Control’s (CDC) main pesticide analytical lab in Atlanta for all HHRA and Heartland Study urine testing, COVID forced a change in plans. This CDC lab was shut down for many months and is only now returning to service. It faces a huge backlog in essential testing and cannot work any HHRA samples into its workflow for many months.

So our team explored other options and were fortunate to learn of the new herbicide-testing capabilities of  CTQ, a new partner in the Heartland Health Research Alliance. The CTQ lab in Quebec serves many of the same functions in Canada as our CDC in the US. It has the world’s only vetted method that detects both glyphosate and its major metabolite AMPA, as well as another common herbicide, glufosinate, and its major metabolite.

CTQ is also going to work with us to develop a new method to measure 2,4-D and dicamba in Heartland Study urine samples. Exposures to these two high-risk herbicides are rising across the Heartland. Both have been linked to cancer and reproductive and developmental problems.

Our first shipment has just arrived at CTQ — about 580 samples of frozen urine from the nuMom2b Nested Case Control Cohort Study (nuNCCS). This research is “nested” within a larger, already completed study on first time moms and their babies.

We will measure herbicide levels in stored urine samples from the nuMoM2b study, allowing us to assess whether moms enrolled in this study with higher herbicide levels in their urine were at higher risk for adverse birth outcomes.

We are also collecting urine from moms and babies enrolled in The Heartland Study, and will be sending these samples to CTQ for analysis. We are excited for this new partnership as we work to improve analytical methods available for measuring human exposure to pesticides and lower the cost per sample tested. Progress is being made on both fronts thanks to the great team of analytical chemists at CTQ.

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