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Dr. Paul Winchester is the director of the Neonatal Intensive Care Unit at Franciscan Health Hospital in Indianapolis, IN and a Co-Principal Investigator of HHRA’s flagship project The Heartland Study.

Archived Blog Posts
  • Eaters Deserve More Complete Information About Nutrition and Health Impacts on Food Labels  

    Multiple lines of evidence point to consumer food choices as major contributors to diet-related disease, and poor health and fitness. In a peer-reviewed journal article published today, authors Chuck Benbrook and Robin Mesnage cite studies indicating that “Some 90% of the estimated USD 4.3 trillion in annual health care costs in the US is triggered or made worse by poor food quality and diet-related disease.” Benbrook is the founder and former executive director of the Heartland Health Research Alliance (HHRA). The authors recommend novel metrics on both the nutrient density of food, and how to more accurately and usefully characterize the degree of food processing and its impacts on public health. The article is open access in the journal Foods and entitled “Enhanced Labeling to Promote Consumption of Nutrient Dense Foods and Healthier Diets.” The core nutrient density metric is a ratio: the percent of daily nutrient needs satisfied by a serving of food relative to the percent of a 2000 calorie daily diet taken up by the serving of food. This single metric is unmatched in comprehensively reflecting the nutritional quality of food. A graphic option to convey the metric on packaging is presented in Figure 3 in the new paper: A novel graphic is presented in Figure 5 to which integrates both the nutrient density and food processing metrics and graphics in a single graphic, shown below. The impacts of ultra-processed food (UPF) on public health outcomes is among the hottest topics in nutrition, medical, and public health journals, and media coverage on food quality and health outcomes. At the request of the journal, the authors developed a video abstract that explains the paper’s goals, methods, and key findings and recommendations. The authors conclude their paper with these observations: Transparent and accurate food product-specific ingredient and nutrient composition data should determine the content of nutrition health labeling. Efforts to soften the message should be resisted in light of the overwhelming need for new food labels that help bring about substantial improvements in food nutritional quality and dietary choices. Benbrook and Mesnage’s paper builds on public comments HHRA submitted in response to the US Food and Drug Administration (FDA) proposed rule in 2023 to update the definition of the term “healthy” on food labels. The proposed role would require foods labeled “healthy” to contain minimum amounts of foods recommended by USDA’s Dietary Guidelines, and to limit saturated fat, sodium, added sugar and other less healthy nutrients. Entitled “Food Labeling: Nutrient Content Claims; Definition of Term `Healthy’”, the comments recommended new  nutrition/health messaging on the front of food packaging. Co-authors of comments included the chair of HHRA’s Policy Advisory committee Dr. Kathleen Merrigan, HHRA science advisors, and other experts working on how changes in farming systems and technology can increase the nutritional quality of food: Dr. Hannah Flower, Dr. Donald R. Davis, Dr. David Montgomery and Anne Biklé. In the comments, the authors introduced “NuCal” as a name for their new system. Resources HHRA February 2023 comments to the FDA. Benbrook and Mesnage (2024). Enhanced Labeling to Promote Consumption of Nutrient Dense Foods and Healthier Diets, Foods. https://doi.org/10.3390/foods13213377 Video Abstract: “Enhanced Labeling to Promote Consumption of Nutrient Dense Foods and Healthier Diets”

  • HHRA Weighs in on Key Pesticide Issues Under Review by the National Organic Standards Board

    HHRA and ORG-Tracker, represented by Dr. Chuck Benbrook and Dr. Brian Baker, submitted comments to the Agricultural Marketing Service at the USDA in advance of the National Organic Standards Board (NOSB) meeting in Portland, Oregon, from October 22nd to 24th, 2024. Drs. Benbrook and Baker will both attend the conference and deliver public comments. ORG-Tracker is a project carried out by HHRA. It aggregates pesticide residue data from inspections of organic farms carried out by certifiers. The tables generated by ORG-Tracker utilize the results of certifier testing to compare residue frequency and risk levels to food produced on conventional farms. The team is working to more effectively highlight gaps and challenges faced by certification agencies to answer questions like What crops should we be testing, and where? Is a pesticide residue found in an organic sample likely caused by accident, pesticide drift, or an intentional and illegal application? How can we modify organic programs to better mitigate risk? The comments delivered to the USDA discuss risk-based certification, pesticide residue testing, and policies impacting the incorporation of so-called inert ingredients in the biopesticides approved for use on organic farms. They argue for a more rigorous, comprehensive, and health-focused approach to risk oversight. Regarding residue testing, they advocate for more expansive and effective data aggregation to inform consumers and the organics community. Finally, for inert ingredients, they recommend further review of current policy, including increased transparency of ingredients in pesticide products. Thank you to Drs. Benbrook and Baker for your advocacy and hard work!   The three sets of comments are posted on HHRA’s website as part of our policy program: Comments to the NOSB on the Risk-Based Certification Discussion Document Under Consideration During the October 2024 Meeting in Portland, Oregon Written Comments on the NOSB Discussion Document “Residue Testing for the Global Supply Chain” Comments on the Inert Ingredients in Organic Pesticide Products Proposal dated August 13, 2024   Drs. Benbrook and Baker also submitted and presented comments at the Spring 2024 meeting of the NOSB, which are available on HHRA’s Policy and Regulatory Reform page.

  • Dr. Kimberly Yolton joins HHRA board

    Dr. Yolton is a developmental psychologist and epidemiologist serving as Professor of Pediatrics at Cincinnati Children’s Hospital Medical Center. Her interests include exposures and experiences that may alter a child’s developmental trajectory from infancy through adolescence. She collaborates on research projects on typical child development as well as those focused on the impact of exposures to environmental toxicants, opiates and stress during early development.

  • Paul Hartnett, HHRA’s Executive Director

      Paul Hartnett has served as HHRA’s CFO since our founding . With the departure of Russell King, Paul has now joined the board and Executive Director. We thank Russell for his service and wish him the best in his future endeavors.

  • Heartland Study Enrolls 1,000th Mother-Infant Pair

    July 19, 2024 – In June of this year, the Heartland Study achieved a major milestone, enrolling its 1,000th mother-infant pair. Enrollment is now at 50% of goal. The objective of the Study is to help fill major gaps in our understanding of the impacts of herbicides on maternal and infant health. Currently in Phase 1, the Study is focused on evaluating associations between herbicide concentrations in body fluids and tissue samples from pregnant women and infants, and pregnancy/childbirth outcomes. Phase 2 is designed to evaluate potential associations between herbicide biomarkers and early childhood neurological development. Much appreciation for the mothers enrolled, and the entire Heartland Study Team including scientists, support staff and clinicians for this tremendous achievement, and for our funders to making this work possible. Read more about the study including peer-reviewed studies published in Chemosphere and Agrichemicals at our publications  page. The investment required to conduct this study exceeds $1 million each year. You can support this important work by making a donation here.

A Worried Doctor Takes Action for Our Babies

Apr 22nd, 2021
Apr 22nd, 2021
Dr. Paul Winchester is the director of the Neonatal Intensive Care Unit at Franciscan Health Hospital in Indianapolis, IN and a Co-Principal Investigator of HHRA’s flagship project The Heartland Study.

There seemed to be too many sick babies in the hospital.

That’s what Dr. Paul Winchester observed when he started working as the director of the Neonatal Intensive Care Unit (NICU) at Franciscan Health in Indianapolis in 2001.

Dr. Paul Winchester, Heartland Study Co-PI

Winchester had overseen hospital nurseries in many regions of the country before moving to Indiana. He had a good sense of how many troubled pregnancies and birth defects to expect in a given month in a community hospital.

But there in a hospital in the Heartland, he was overwhelmed at the numbers of babies needing medical care. And he was curious: Did Indiana have more birth defects than other states outside the Midwest?

The answer, he learned, was yes, some birth defect rates were higher in Indiana. His next question was why?

The answer to that question led Winchester to the many farms that sprawl across Indiana and the larger region of the U.S. Midwest. Several published scientific studies have demonstrated that women who conceive their children during the months in which agricultural chemicals are in high use are more likely to experience shorter pregnancies or give birth to smaller babies. A few studies have also detected a correlation between exposure to pesticides such as those used in agriculture and higher rates of some birth defects. (See this White Paper for a more detailed discussion of the trail of science Dr. Winchester followed.)

There is also evidence that exposure to these pesticides may carry forward across generations because of a biological process known as transgenerational epigenetic inheritance.

Winchester’s concerns and questions led him to join The Heartland Study team and its scientists and clinicians, working to determine whether or not rising use of herbicides negatively affects the health and development of children, possibly for generations to come.

At The Heartland Study team meeting in Indianapolis in 2019, Winchester gave The Heartland Study team a tour of the NICU at Franciscan Health Hospital, which was at capacity with babies needing intensive medical care. Seeing those little bodies fighting for a healthy start was an impactful moment.

Knowing that Dr. Winchester is there every day, walking those halls, keeps us humbled, driven and grounded in the roots of what The Heartland Study is about: protecting the health of families in the Midwest and beyond.

About The Heartland Study

HHRA’s flagship project, The Heartland Study, is the first-ever study to track heritable, epigenetic changes resulting from herbicide exposure in a human population. In our research, we will pioneer new, critically-needed methods to identify the impacts of prenatal and early life herbicide exposures.

Our hope is that we can generate knowledge that guides changes in the ways farmers control weeds by focusing new science on the most important outcome: healthy babies that develop normally and retain their full potential for productive and healthy lives. Learn more about our efforts and how you can support our mother-infant enrollments.

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