An increasingly popular way to manage charitable giving is by donating cash, securities, or other assets into a donor-advised fund (DAF), from which you will receive an immediate tax deduction. From this, donors can recommend grants to IRS-qualified nonprofit organizations.  DAFs are one of the easiest and most tax-advantageous ways to “grow” resources earmarked for future charitable giving.  The HHRA is an IRS-qualified organization, and we encourage you to use your DAF, if you have one, to support our mission. You can find three simple steps to supporting our research via your DAF here.  Simple and convenient, your DAF can have genuine effects on the health of mothers, babies, and future generations.  Thank you!

Dicamba and 2,4-D in the Urine of Pregnant Women in the Midwest: Comparison of Two Cohorts (2010–2012 vs. 2020–2022) Abstract Currently, there are no known human biomonitoring studies that concurrently examine biomarkers of dicamba and 2,4-D. We sought to compare biomarkers of exposure to herbicides in pregnant women residing in the US Midwest before and after the adoption of dicamba-tolerant soybean technology using urine specimens obtained in 2010–2012 from the Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-be (N = 61) and in 2020–2022 from the Heartland Study (N = 91). Specific gravity-standardized concentration levels for each analyte were compared between the cohorts, assuming data are lognormal and specifying values below the LOD as left-censored. The proportion of pregnant individuals with dicamba detected above the LOD significantly increased from 28% (95% CI: 16%, 40%) in 2010–2012 to 70% (95% CI: 60%, 79%) in 2020–2022, and dicamba concentrations also significantly increased from 0.066 μg/L (95% CI: 0.042, 0.104) to 0.271 μg/L (95% CI: 0.205, 0.358). All pregnant individuals from both cohorts had 2,4-D detected. Though 2,4-D concentration levels increased, the difference was not significant (p-value = 0.226). Reliance on herbicides has drastically increased in the last ten years in the United States, and the results obtained in this study highlight the need to track exposure and impacts on adverse maternal and neonatal outcomes. Keywords: pesticide; exposure; 2,4-dichlorophenoxyacetic acid; human biomonitoring You can read the paper here.

Farmers say they are losing their battle with weeds at a time when growers are grappling with inflation and extreme weather linked to climate change. Crop-killing weeds such as kochia are advancing across the U.S. northern plains and Midwest, in the latest sign that weeds are developing resistance to chemicals faster than companies including Bayer and Corteva  can develop new ones to fight them. In many cases weeds are developing resistance against multiple herbicides, scientists said. Read the Reuters report here.  Read an earlier post by the HHRA board chair on the problem of resistant weeds here.

We are publicly recruiting for board positions to ensure that we move beyond our immediate networks and honor our ongoing commitment to creating a board that is diverse in its composition, inclusive in its culture, and equity-focused in its approach to how it views its mission, its work, and the communities it serves. Our board members are the fiduciaries who steer the HHRA toward a sustainable future by adopting sound, ethical, and legal governance and financial management policies, as well as by making sure the HHRA has adequate resources to advance its mission. The Heartland Health Research Alliance (HHRA) is a 501(c)(3) organization founded in 2020 and dedicated to creating a new future in which cultivating health is the priority of farming. Our mission is to help inform the decisions shaping agriculture by advancing research on the health effects of food and farming. The HHRA seeks to fill vacancies on its board with qualified volunteers who, in addition to the standard roles and responsibilities (see below) of a board member, will be active advocates and ambassadors for the organization. Preferred qualifications 1. Professional experience in public health, medical research, epidemiology, toxicology, or organic farming, 2. A network or experience, or both, that may facilitate grant seeking and fundraising. 3. Commitment to the scientific method and the integrity of research. Essential information 1. The board of the HHRA is a volunteer board. 2. Each term is for three years, to which members can be re-elected once. 3. The board meets four times a year via the Internet. Expectations The HHRA expects each board member to honor the HHRA values and mission, act in the best interest of the HHRA, prepare for the board meetings by reading the agenda and reports, participate in the board meetings, and identify personal and professional connections for HHRA fundraising, grant-seeking, and policy influence. Process 1. To apply to volunteer, please send your CV and a one-page cover letter providing your name, contact information, and a description of either which of the preferred qualifications (above) you will bring to the HHRA or how your unique qualifications can help the HHRA.  Send these materials to Russell K. King, HHRA executive director, at rking@hh-ra.org . 2. Qualified applications will be reviewed by the current board, which will vote on whether to seat a volunteer as a member. (The next board meeting is in February 2024.) 3. The recruiting process will remain open until all seats are filled. Standard board member duties 1) Board members should advance the mission of the organization Overall, spreading awareness for your mission will promote growth and empower your team to flourish in its work. 2) Board members should prepare for and attend board meetings Review the agenda in advance. Everyone should understand all matters on the agenda heading into the meeting. Participation in discussions is a big part of why you choose someone for a role on the board. Fulfilling these duties is part of acting in good faith for any board member. 3) Board members hire, set compensation for, support, and collaborate with the executive director Hiring and supporting the executive director is one of the most important board member responsibilities.  The executive director is the professional hired to as bring nonprofit leadership and operational expertise to the HRRA’s daily operations and to advice and educate the board on matters relating to nonprofit governance and operations, so this board role is crucial to the organization’s health. 4) Board members are responsible for recruiting new members Drawing on your professional and personal networks, seek new members who have needed skills and qualities that are missing from the current board. 5) Every board member must fulfill three specific core legal responsibilities. Duty of Care Attending meetings and actively participating. Communicating with the executive director and other board members. Following through on assignments.. Supporting programs. Duty of Loyalty Support HHRA’s mission. Be a loyal ambassador for HHRA’s cause. All activities and decisions should be in the best interest of the organization, not in the best interest of the individual board member. Support the HHRA executive director. Duty of Obedience Adhere to HHRA’s bylaws, policies, and board decisions.

From the British Food Journal Findings show that perceived distributional, procedural and interactional fairness mutually interact with the perceived trustworthiness of business partners and that both contribute to building personal, organisational and institutional trust. Qualitative data support the conceptual model and show that trust is a valuable relational resource that affects relationship quality and the willingness to collaborate and to take risks in times of uncertainty.   More here.

By Thomas Green, PhD, chair, HHRA Board of Directors Consumer Reports (CR) published a cover story today on pesticides on fruits and vegetables in the US food supply. CR concluded that “20% of the 59 fruit and vegetables tested posed a high risk from pesticides.” Blueberries, green beans, watermelons, bell peppers, potatoes, kale, and mustard greens were among the 12 highest-risk foods. What’s going on here? The United States Department of Agriculture (USDA) annually publishes a report with results from pesticide residue sampling completed two years prior. In January, the USDA’s report assured consumers that 99% of more than 10,000 samples of foods collected in 2022 had pesticides at or below EPA-set legal limits. To add to the confusion, the EWG (formerly Environmental Working Group) follows up each USDA report with its “Shopper’s Guide to Pesticides in Produce” and its widely promoted Dirty Dozen and Clean 15 lists. This year, EWG “determined that 75 percent of all conventional fresh produce sampled had residues of potentially harmful pesticides.” Blueberries, green beans, bell peppers, potatoes, kale, and mustard greens made the EWG’s Dirty Dozen, but not watermelon. Grapes and peaches also made the Dirty Dozen but didn’t make CR’s list of 12 highest risk foods. Three very different perspectives, yet all three organizations use the same data source! Residue data are generated by the USDA, which collects and tests domestic and imported food samples from our food distribution system in multiple states each year. Why the discrepancy in findings? Here’s the story The USDA uses “residue tolerances” established by the US Environmental Protection Agency (EPA). Residues under the tolerance level are regarded as safe. Foods with pesticide residues over the tolerance render the food adulterated. Food declared as such is supposed to be removed from the marketplace but fresh produce rarely is. The EPA tracks total dietary exposures to a given pesticide based on all tolerances that have been approved and by law must determine that there is a “reasonable certainty of no harm” from total exposures. As reported by the USDA this year, of the 10,665 samples collected in 2022, 325 had pesticide residues exceeding the tolerance or present in the absence of a tolerance, or about 3% in total. A third of the samples with over-tolerance, presumptively unsafe residues were US-grown; two-thirds were imported foods. In 2022, 27% of samples tested had no detectable residues. The EWG uses pesticide residue detections, so regardless of the tolerance level set for a pesticide, each residue detected is counted. A food makes the Dirty Dozen list if it is among the foods with the highest number of pesticide residues. Residues of some pesticides known to pose health hazard are weighted more heavily. The EWG typically lumps US and foreign-grown food in their report. In the report released today, CR analyzed USDA data on 59 foods in more than 26,000 samples tested by the USDA over seven years (2016-2022). CR used EPA-set toxicity thresholds for most pesticides but added the full 10-fold safety factor called for in federal law to several more high-risk pesticides than the EPA does. CR scientists consider the EPA’s tolerances to be too high for some pesticides, so they developed these lower limits for “pesticides that can harm the body’s neurological system” or are suspected of interfering with human hormones. The analytical work supporting the CR report was completed by a team led by the HHRA’s founder and first executive director Chuck Benbrook, and grounded in analyses conducted using the Dietary Risk Index (DRI) system currently housed on the HHRA’s website. The DRI is also included in the Pesticide Risk Tool, developed by a team I led and housed at the IPM Institute. I co-founded the IPM Institute in 1998 where our Sustainable Food Group continues to work with food companies and supply chains to reduce pesticide risks among other initiatives. So which report wins the day? All three have value, and all three point to opportunities for improvement. Without the USDA’s highly regarded pesticide residue testing program, efforts to reduce the frequency of high-risk residues would be like shooting in the dark. Of the three analyses, the USDA’s report represents the least conservative approach to estimating risk. Yet the level of tolerance violations reported by the USDA represents hundreds of millions of presumptively unsafe servings of food in the US every year! The EWG and CR take a more conservative approach to estimating and avoiding risk. Both organizations recognize that not all potential risks have been identified or accounted for in EPA risk estimates. For example, we all ingest multiple pesticide residues daily via food and drink, but their combined risk is not taken into account by the EPA. CR’s approach is more science-based and more closely aligned with the EPA’s dietary risk assessment. CR’s methodology is driven by measured residue levels, EPA-set exposure thresholds based mostly on animal studies, and standard food serving sizes. Not all pesticide residues pose equal risk, in fact they vary by over 10,000-fold! What’s the bottom line? All three organizations recommend that everyone should eat lots of fresh fruits and vegetables. The benefits to health outweigh the risks of pesticide exposure. The EWG recommends consumers buy organic versions of its Dirty Dozen. CR recommends limiting consumption of foods they have identified as highest risk to ½ serving per day or less, and buying organic when available and affordable. A common question is, “Can I remove pesticide residues by washing?” Before testing, food samples used in these reports are at a minimum lightly washed. Additional washing may help but will not achieve anywhere near our potential to reduce risk. It’s important to highlight that US-grown conventional food samples have generated fewer tolerance violations year after year compared to imported food, and that organic foods have also consistently generated far fewer violations than conventionally grown samples. In addition, the overall pesticide risk reduction achieved for birds, bees, and people since passage of the Food Quality Protection Act in 1996 has been astounding and readily […]

By Russell K. King, HHRA Executive Director Less than a week ago, the academic publisher Sage Journals retracted studies that questioned the long-established safety record of mifepristone. In December. Nature ran a piece noting that, in 2023, more than 10,000 scientific papers–a record number–were retracted. Not understanding the data, the anti-science voices decry the retractions as proof of corruption in the research community. Misunderstanding scientific publishing is an old and common problem. Early in my career, I was editor of a peer-reviewed medical journal, and part of my job was to translate the scientific language into messages more easily understood by nonscientific readers. I offer here a guide to reading scientific papers when you’re not a scientist. This method is not the only method, and I didn’t create it, but I’ve found it useful. Before I do, however, I hasten to say that the wave of retractions last year does not indicate a wave of fraud in science. The number of journals in publication rose from 1 million in 1997 to 3 million in 2020, yet the average number of retractions per journal has remained largely flat during that time.  Half of the retractions are for reasons other than fabrication, falsification, or plagiarism. The data seem to say the scientific community has stepped up.  Scientists are pressuring journals, and, in turn, journals are improving their policing of papers after publication. Reading scientific papers Step by step: 1. read the abstract to get the general idea of what the paper is about; 2. read the figures and legends to understand the data (then look to see whether they align with the conclusions in the abstract); 3. read the discussion, where the authors summarize and interpret the data (then see whether it aligns with the data in the figures and the overview in the abstract); and 4. if it’s not your field of expertise (true for most of us, even if it’s hard to admit), read the introduction to get a feel for what the relevant literature says; 5. if you’re evaluating how they got from the data to the conclusions, read the discussion (are they using standard methods, missing controls, using a representative sample and a control group, etc.?); and 6. read through a few references to see whether they say what the authors claim they do (padding the references with papers that do not fit is often a way to build false credibility). Red flags As you’re reading, keep your eyes open for signs that should cause you to pause and question the paper’s validity. Red flags don’t necessarily mean the paper is untrustworthy, just that we should not draw conclusions without digging deeper.  Some such red flags are: 1. the author has no expertise in the subject of the paper (is their degree in a relevant field, have they worked in the field, have they previously published in the field in reputable journals?)–crossovers are not uncommon, but these will typically have a coauthor who has credible expertise; 2. the references are old, meaning fewer than six citations from the past five years; 3. the results asserted are not closely tied to the data or are not placed in context with other studies; 4. the conclusions contradict the literature or general scientific consensus–advances happen, but this should prompt us to withhold judgment until we get more information; 5. funders are not disclosed; 6. conflicts of interest are not declared; and 7. the results have not been peer reviewed. Know yourself Because science and anti-science have become such powerful forces in cultural and political differences, it’s vital that we check ourselves as we read and evaluate scientific papers. No matter how well trained we are in critical thinking, no matter how separate we think we are from the cultural and political echo chambers around us, we are still human and we are still given to myriad thinking errors. To deal with the overwhelming amount of information our brains take in, our brains seek shortcuts to lessen the burden. Sometimes these shortcuts are helpful; too often they are not. At minimum, we process information through our personal confirmation bias and a complex, overlapping, ever-changing matrix of internal filters made of everything from our DNA to what we had for lunch. We must ask ourselves–more often than is comfortable–whether our understanding of what we’re reading is being distorted by our own emotions, preferences, prejudices, assumptions, and hopes. This requires us to be honest with ourselves about our emotions, preferences, prejudices, assumptions, and hopes. Read! Science is always emerging, never static. By the moment, it grows ever broader, deeper, more beautiful, more fascinating, and more important to our lives. We depend on science to bring us new information and understanding, to correct the errors of our past and–yes–to retract papers that are erroneous. The 10,000 retractions of 2023 should enhance, not undermine, our appreciation for the men and women of science who share their work with us.  What’s happening in science is exciting, and I promise you that reading about it is more than worth the effort.    

Planned giving is the process of donating planned gifts, also known as legacy gifts, which are contributions that are arranged in the present and allocated at a future date. Commonly donated through a will or trust, planned gifts are usually granted when a donor passes away.  If you’d like to plan a gift for to support the important work of HHRA, you may use this form.  Thank you. Tax benefits:  Donors can contribute appreciated property, like securities or real estate, receive a charitable deduction for the full market value of the asset, and pay no capital gains tax on the transfer.  Donors who establish a life-income gift receive a tax deduction for the full, fair market value of the assets contributed, minus the present value of the income interest retained; if they fund their gift with appreciated property they pay no upfront capital gains tax on the transfer.  Gifts payable to the HHRA upon the donor’s death, like a bequest or a beneficiary designation in a life insurance policy or retirement account, do not generate a lifetime income tax deduction for the donor, but they are exempt from estate tax. More information: For those who wish to make legacy gifts that are guaranteed to support their own philanthropic interests and intentions, planned or deferred gifts may be most effective. Planned gifts require more planning than most current gifts or income or equity, often including legal and accounting counsel from a donor’s trusted advisors. Because these gifts produce philanthropic benefits to recipient organizations, there may be benefits to the donors or their heirs via reductions in state or federal income, capital gains, estate, or gift taxes. There are many ways to make planned gifts, the most simple of which are life insurance policies, designated distributions from retirement funds, or bequests, where donors designate a percentage or a specific amount of their estate to the recipient charity.  Specific amounts are preferable, as they do not require a full valuation of the estate before distribution can be made. For donors over the age of 70 ½ years who are required to take minimum annual distributions from their Traditional or Roth Individual Retirement Accounts (IRAs), up to $100,000 may be directed to charitable causes, with potentially significant tax savings each year. More complex planned giving arrangements such as charitable gift annuities, charitable remainder unitrusts, charitable remainder annuity trusts, lead trusts and others may provide donors with guaranteed income for the remainder of their lives in exchange for funds transferred to charities now. The gist of most such gift vehicles involves a donor making a current gift to a charity with commensurate tax benefits, the charity paying the donor per agreed-upon terms from those funds in the years that follow, with the remainder of the funds at the donor’s death remaining with the charity in perpetuity.

By Russell K. King, HHRA Executive Director I’m pleased to announce that the HHRA has once again earned the Candid Platinum Seal of Transparency (our first was in 2023)-–an achievement earned by fewer than one percent of US-based nonprofits. The Candid Platinum Seal is the highest level of recognition offered by Candid (formerly known as GuideStar) and is awarded to organizations that meet the highest standards of transparency and accountability. The Candid Platinum Seal demonstrates the HHRA’s commitment to transparency and accountability. Our board, staff, volunteers, and partners believe that by sharing our data, metrics, and strategic priorities with the public, we can build trust and confidence in our organization and our work. To earn the Candid Platinum Seal, non-profit organizations must meet a rigorous set of criteria, including providing complete and accurate information about their mission, programs, finances, and governance on the Candid website, and sharing strategic priorities and information about outcomes.

By Russell K. King, HHRA Executive Director Living, as we do, during an era overwhelmed by misinformation, disinformation, mistrust, grifters, posers, and pretenders, integrity is an increasingly rare and valuable quality. For a nonprofit organization like the HHRA, integrity is essential. By funding the Heartland Study, we are seeking the answer to a controversial question:  Are there health problems for mothers and infants that correlate to higher exposure of agricultural chemicals? Why is that controversial? Because there are people who insist they already know the answer and, regardless of whether they insist it’s “yes” or “no,” they prefer we don’t ask. They have vested interests in the answers they promote and fear an unbiased scientific inquiry may produce an answer that does not support those interests. A vested interest—”a strong personal interest in something because you could get an advantage from it,” according to the Cambridge Dictionary—is deadly to integrity. We don’t know whether we’re being told the truth or being told what advances your interest, so we can’t fully believe you. Doubt will endure and undermine your message. Thankfully, the HHRA has no vested interest in the outcome of the Heartland Study. The chair of the HHRA Science Advisory Committee insists we must be “agnostic about the outcome,” and the chair of the HHRA Board of Directors insists we must not “get ahead of the data.”  The principle investigator for the Heartland Study oft reminds us to “always let the science lead.”  As the HHRA executive director, I don’t care what the answer is, but I’m certain the question must be asked. The HHRA and the scientists working on the Heartland Study are not out to prove the answer is yes or no, but to learn whether the answer is yes or no. Likewise, our donors are supporting the effort to find “the” answer not “an” answer. There are no foregone conclusions here. All of which points to the integrity of our mission and our work. Integrity is demonstrated and enhanced by transparency, which is why the HHRA makes public its IRS determination letter, audited financials, bylaws (including our conflict of interest policy), strategic plan, gift acceptance policy, volunteers and staff, and the Heartland Study’s methods paper, published in a peer-reviewed journal.  Such transparency has already earned the highest award from Candid. Integrity yields many positive results.  First, the people and foundations that support the HHRA can know that the money they donate is being used for its stated purpose.  Second, and more importantly, the people who will eventually learn of our outcomes and recommendations, if any, can know that they can trust what they’re being told. That trust will make it more likely that our work will be used in improving public health.  And that is what it’s all about.